ESPN’s Josh Weinfuss reports the Cardinals “assume James Conner’s right ankle injury is severe enough to end his season.”

Weinfuss notes that an official prognosis hasn’t been made, but the team clearly fears the worst. Conner suffered a brutal injury in Sunday’s loss and had to be carted from the field. While he hasn’t officially been ruled out for any length of time, it sounds like the team is preparing to be without him for the rest of the season if tests confirm the worst. It’s a tough blow for Conner, 30, who has rushed for 1,000-plus yards in back-to-back seasons. If he is lost for the season, Trey Benson could be forced into a decent bell cow role while Emari Demercado gets elevated to RB2 duties.