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Lopez, the Cardinals’ starting nose tackle, will play through a questionable designation after suffering toe and ankle injuries last week. The Rams’ ground game should still play well, but Lopez will make them work a little harder for yardage than they otherwise might have had to. Cardinals S Andrew Wingard (groin) and CB Max Melton (knee/hand) are also active. The Cardinals declared QB Joey Aguilar, CB Starling Thomas, LB Eku Leota, OL Jayden Williams, OL Jon Gaines and C Hjalte Froholdt inactive for Week 10 against the Rams. Playing without Froholdt, their starting center, and Williams, their current starting left tackle, is unfortunate.

The deal includes $7 million guaranteed. 28-year-old Lopez is returning to Arizona after a one-year sojourn in Motown. A space clogger in the middle of the defense, Lopez will find a rotational role on early downs in the desert, but nothing more.

A 2021 sixth-round pick of the Texans, Lopez was cut by Houston on the eve of the 2023 season. He then managed to become a Cardinals mainstay as a rotational interior lineman. That is what he will remain in Detroit during his age-28 season.