NFL · 2021 Season
2021 Buffalo Bills
11-6 · 1st AFC East
PTS/G
29.8
OPP/G
18.3
PASS Y/G
234.2
RUSH Y/G
116.3
Regular season
NFL · 2021 Season
11-6 · 1st AFC East
PTS/G
29.8
OPP/G
18.3
PASS Y/G
234.2
RUSH Y/G
116.3
Regular season
| Date | Opponent | Score | W/L | Record |
|---|---|---|---|---|
| Sun, Jan 23 | KC @Kansas City Chiefs | 36-42 | L | 1-1 |
| Sat, Jan 15 | NE vsNew England Patriots | 47-17 | W | 1-0 |
| Sun, Jan 9 | NY vsNew York Jets | 27-10 | W | 11-6 |
| Sun, Jan 2 | AT vsAtlanta Falcons | 29-15 | W | 10-6 |
| Sun, Dec 26 | NE@New England Patriots | 33-21 | W | 9-6 |
| Sun, Dec 19 | CA vsCarolina Panthers | 31-14 | W | 8-6 |
| Sun, Dec 12 | TB @Tampa Bay Buccaneers | 27-33 | L | 7-6 |
| Mon, Dec 6 | NEvsNew England Patriots | 10-14 | L | 7-5 |
| Thu, Nov 25 | NO @New Orleans Saints | 31-6 | W | 7-4 |
| Sun, Nov 21 | IN vsIndianapolis Colts | 15-41 | L | 6-4 |
| Sun, Nov 14 | NY@New York Jets | 45-17 | W | 6-3 |
| Sun, Nov 7 | JA @Jacksonville Jaguars | 6-9 | L | 5-3 |
| Sun, Oct 31 | MI vsMiami Dolphins | 26-11 | W | 5-2 |
| Mon, Oct 18 | TE @Tennessee Titans | 31-34 | L | 4-2 |
| Sun, Oct 10 | KC@Kansas City Chiefs | 38-20 | W | 4-1 |
| Sun, Oct 3 | HO vsHouston Texans | 40-0 | W | 3-1 |
| Sun, Sep 26 | WA vsWashington Commanders | 43-21 | W | 2-1 |
| Sun, Sep 19 | MI@Miami Dolphins | 35-0 | W | 1-1 |
| Sun, Sep 12 | PI vsPittsburgh Steelers | 16-23 | L | 0-1 |